Trasmitting Layer 2 Frames Across WANs

I have an audio interface (Metric Halo ULN-2) that connects via ethernet (layer 2, no IP layer) to a Mac (no PC support for the App that controls settings etc).
It can also connect via usb, I can use it as an audio interface for my pcvia USB but can’t control parameters unless it’s connected to a mac via ethernet and running MIO Console App at the same time…
I am wondering if I can take the unit with me to another location, connect remotley to my mac at home running the necessary app and trasmit frames via zerotier between the mac and my audio interface.
So far, I’ve added both computers to zerotier and can ping them from either side.
Can I achieve the next step of trasmitting frames and how?

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